| Definition:
The red bone marrow is the site of hematopoiesis, or blood cell formation.
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 Structure:
The red bone marrow is located primarily in the axial
skeleton (vertebra, sternum and ribs), the pectoral
and pelvic girdles and the proximal epiphyses
of the femur and the humerus
of adults. It is composed of a network of connective tissue around a set
of blood capillaries. This network
contains stem cells and immature blood cells, macrophages, fat cells, and
reticular cells.
 Function:
Stem cells, called hemocytoblasts, are the source of the Ôcommitted
cellsÕ, the proerythroblasts, the myeloblasts and the monoblasts
series of stem blood cells. Once committed, a pathway develops for making
red blood cells in the marrow, from proerythrocytes to erythrocytes. The
erythrocytes, called red blood cells are released into the blood
stream. Myeloblasts develop into leucocytes and lymphocytes,
and monoblasts, into monocytes. The macrophages generate platelets.
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