Name: Target glands

Definition: Target endocrine glands are the sites of action for trophic endocrine hormones.

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Structure: Target glands for trophic endocrine hormones from the hypophysis are located throughout the body. The are the thyroid and the parathyroid glands in the neck, the Islets of Langerhan in the pancreas and the adrenal glands in the back, and the ovaries and the testis in the pelvis. The adrenal glands have a cortex with three zones; the glomerulosa, fasciculata, and the reticularis, and a medulla. The medulla is made up of chromaffin cells, a part of the sympathetic nervous system. The rest are stimulated by the trophic hormones from the adenohypophysis.


Function: The target glands of the endocrine system secrete active hormones into the circulation. These hormones are thyroxine, calcitonin, parathormone, insulin, glucagon, somatostatin, aldosterone, corticosterone, dehydroepiandrosterone-sulfate, testosterone, androstenedione, estradiol, and progesterone. In addition, epinephrine and norepinephrine are secreted by the adrenal medulla in response to neural signals, and spermatozoa are produced by the testis from the action of FSH on the Sertoli cells. These chemical substances are extracted by their target tissues where their effect can be observed.

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